Football game of the regular season will be between the Detroit Lions and San Francisco 49ers. Here's how to watch.

DFS millionaire Mike McClure shares his top daily Fantasy football picks for San Francisco 49ers vs. Detroit lions on MNF ...

Check out San Francisco 49ers tight end George Kittle's best catches from his 112-yard game vs. the Detroit Lions during Week ...

Jauan Jennings’ ejection and Isaac Guerendo’s cart-off knee injury added to the 49ers’ season-long macabre in Sunday’s 47-24 ...

The San Francisco 49ers just lost 47-24 to the Arizona Cardinals. Here are the 49ers' grades for this performance.

The Detroit Lions could have rested their starters on Monday night against the San Francisco 49ers with the knowledge that it ...

This week’s Monday Night Football game features the Detroit Lions visiting the San Francisco 49ers. The Lions have been the ...

Ahead of their game against the Detroit Lions, it’s time to release our San Francisco 49ers Week 17 predictions.

It's a postseason episode this week! Super Bowl LVI champion and Los Angeles Rams legend Andrew Whitworth joins Ricky Hollywood to discuss the push into the playoffs, what to expect against the ...

(AP Photo/Chris Szagola, File) FILE -Former Philadelphia Eagles wide receiver DeSean Jackson poses with the WWE belt prior to ...

Travis Kelce and Taylor Swift are going strong, Josh Allen popped the question, Trevor Lawrence and his wife are expecting, while Patrick and Brittany Mahomes family is growing.

Charvarius Ward isn't sure he'll return to the San Francisco 49ers, saying that there's been a lot of "trauma" over the past ...